6 Benefits
1Stress Relief/
Relaxation Effect
GABA could help fight the stress and anxiety, improve relaxation, and reduce anxiety.
Oral Consumption of a beverage containing 50 mg of GABA reduced stress (CgA) and fatigue (cortisol) in subjective and objective assessments. The percentage of correct responses in Arithmetic tasks was also found to be increased.
T. Kanehira, et. al., J Nutr Sci Vitaminol. 2011;57(1):9-15.
Oral consumption of 100mg of GABA suppressed the sharp decrease in brainwave activity caused by stress.
Oral consumption of 100mg of GABA improved relaxation effect.
(increased alpha waves, decreased beta waves)
Adham M. Abdou., et. al., Biofactors. 2006;26(3):201-8.
2Improvement of Sleep
GABA improves overall quality of sleep. Our human study showed that GABA absorbs in our body within 30 min. Therefore, taking GABA supplement 30-60 min before going to bed is helpful to impart good sleep.
Consumption of 100 mg GABA for a week significantly shortened sleep latency and increased the total non-rapid eye movement (non-REM) sleep time. Questionnaires showed that subjects receiving GABA experienced its positive effects on sleep.
A. Yamatsu, et. al., Food Sci Biotechnol. 2016;25(2):547-551.
100 mg of GABA was given to elderly people for 4 weeks. The results showed that there was an improvement in the quality of sleep such as sleep latency and quality of sleep, drowsiness in the morning, and recovering from fatigue in the GABA group. Furthermore, the frequency of night urination significantly decreased in the GABA group.
Combination of GABA and Apocynum venetum Leaf Extract showed synergistic effects to improve the quality of sleep.
3Improvement of
Cognitive Health
Large scale human clinical studies with 120 men and women revealed that PharmaGABA®︎ improves cognitive health in dose-dependent manner. PharmaGABA®︎ found to improve cognitive functions such as logical thinking, working memory, long-term memory, sustained attention, visuospatial and construction ability, mental health and so on.
| Improved cognitive functions by GABA | Logical thinking | Working memory | Sustained attention | Visuospatial & Construction ability | Long-term memory | Vitality | Mental health |
|---|---|---|---|---|---|---|---|
| 100 mg | |||||||
| 200 mg |
*PharmaGABA® is the first ingredient reported to improve logical thinking.
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Logical thinking
An improvement in logical thinking means an improvement in ability to thinking rationally and derive a solution or an answer.
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Working memory
An improvement in Working Memory means an improvement in ability to organize and judge only necessary information in a short-term work, and ability to forget unnecessary one and remember necessary one from the ever-changing information.
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Visuospatial & Constructive ability
An improvement in Visuospatial/
Constructional scores means an improvement in ability to recognize and reproduce the spatial position, shape, and orientation.
4Promotion of Muscle Mass
In combination with protein-source such as whey protein, GABA enhances the fat-free muscle mass. These results are helpful for athletes, bodybuilders for improving their muscle mass. In addition, senior citizens may maintain their muscle mass and would be able to avoid sarcopenia risks with the help of GABA.
21 healthy men were given 10 g whey protein + 100 mg GABA for 12 weeks. Mild resistance training (60% of maximal muscle strength) was performed twice a week. The results exhibited that the combination of whey protein and GABA significantly increased total body fat-free mass compared to whey protein alone.
M. Sakashita, et. al., J Clin Med Res. 2019;11(6):428-434.
5Maintenance of Energy & Vitality
GABA alleviates of decreasing vitality.
Mental stress tasks result in decreased brain activity. A single dose of 100 mg of GABA showed significant increase in vitality scores compared to the placebo group.
A. Yoto, et. al., Amino Acids. 2012;43(3):1331-7.
6Maintenance of Skin Elasticity
GABA maintain skin elasticity. Taking GABA helps prevent rough skin from getting worse.
100 mg of GABA consumption for 8 weeks exhibited significant benefits in maintaining the skin elasticity compared to the placebo group.
